Mixero
The new generation Twitter client for people who value their time and are tired of information noise

IM+ All-in-One Messenger with IM Push
Chat in AIM®/iChat, MSN®/Windows Live™ Messenger, Yahoo!®, ICQ®, Jabber®, Google Talk™,

Sideline
Watch, search and monitor the Twitter public timeline in real-time.

Screentweetr
Screentweetr enables you to quickly post screenshots to a twitter image service.

DestroyTwitter
DestroyTwitter is a robust but compact Twitter application.

Birdshot
Birdshot is a Twitter client stripped down to the basics: send tweets and tell me when I have new

Seesmic Desktop
Seesmic Desktop is an Adobe AIR application for social networking/Twitter-related activities.

SpreadTweet
SpreadTweet is basically a twitter client that look like a spreadsheet.

TwitDoc Desktop Uploader
The TwitDoc desktop uploader makes it easy to share your documents and pictures on Twitter.

TweetDeck
Stay in touch with contacts across Twitter, Facebook and more.